Erickson Lab
Erickson lab focuses on biomarker detection in tissues, with a current focus on identifying clonal evolution of early-stage cancers. The lab develops and applies cutting-edge techniques that allow for spatial molecular characterization of the tumor microenvironment within patient’s tissue specimens. In addition, the lab actively develops novel computational techniques to derive knowledge from the large-scale datasets being generated from these technologies. Our work will result in a better understanding of cancer biology which will lead to improved patient outcomes through improved diagnosis and novel treatments.
Research Themes
Spatial Biology
Genetic sequencing has increased our understanding of tumors. Previous “bulk” sequencing methods read out an average signal from many different cells and can fail to capture the underlying heterogeneity within solid tumors. Single cell analyses were developed to characterize molecular biologies in single cells. While these methods are powerful in identifying biologies at high resolution these approaches dissociate cells, destroying the spatial-cellular relationships these cells have.
Affiliations
HUCC
Helsinki Urological Cancer Research Group centers around the clinical and academic work done at the HUS Helsinki University Hospital and Helsinki University.